Correlation of Mammography Features with Histopathology Findings Using 11-gauge Stereotactic Vacuum-Assisted Breast Biopsy (SVABB) in the Breast Center of St. Luke’s Medical Center – Global City (SLMC-GC)

Objective: To correlate histopathology findings using 11-gauge stereotactic vacuum-assisted breast biopsy with mammography features. This study also aims to evaluate the use of BI-RADS in a local setting, involving a particular group of patients with suspicious mammography findings, which underwent stereotactic vacuum-assisted breast biopsy.

Patients and Methods

All data of women who underwent mammography (Siemens MAMMOMAT Inspiration) and 11 -gauge stereotactic vacuum-assisted breast biopsy (Siemens MammoTest) in the Breast Center of SLMC-GC from January 2010 to December 2015 were recorded by the primary investigator.

Results

Local data show correlation between BI-RADS assessment and histopathology findings. Malignancy rates of 18% for BI-RADS 4A, 24% for BI-RADS 4B and 100% for both BI-RADS 4C and 5 were calculated. However, BI-RADS assessment does not correlate with specific tissue diagnosis. Mammography findings of microcalcifications alone and microcalcifications with architectural distortion correlated with a histopathology finding of either ductal carcinoma in situ or invasive ductal carcinoma. No mammography finding however, correlated with a benign or malignant histopathology finding.

Conclusion

The presence of microcalcifications and/or architectural distortion does not correlate with a benign or malignant histopathology, but microcalcifications and/or architectural distortions, if malignant are likely ductal carcinoma in situ or invasive ductal carcinoma. BI-RADS assessment in this local setting correlated well with a benign or malignant histopathology but shows no correlation with a specific tissue diagnosis