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Refeeding syndrome: incidence of refeeding hypophosphatemia and other electrolyte abnormalities among patients referred to Clinical Nutrition Physicians- a report from a private tertiary care hospital in the Philippines

Jesus Fernando Inciong, Maria Victoria Manuel, Mustofa, Naheeda. MD, Llido, Luisito. MD, Eliza Mei Francisco. MD, Olive Quizon. MD, Marianna Ramona Sioson. MD, Divina Cristy Redondo-Samin. MD, Danilo Del Rosario. MD, Nellie Gundao. MD, Maricar Esculto. MD, Donnabelle Navarrete. RND

Background: The incidence of hypophosphatemia in relation to refeeding syndrome is well-recognized in other countries. Though there has been no consensus yet as to the exact definition of refeeding syndrome, refeeding hypophosphatemia remains to be a hallmark. In the Philippines, there is no report yet on in-hospital tertiary care hypophosphatemia among those referred to Clinical Nutrition physicians. This study aims to describe the incidence of refeeding hypophosphatemia among patients referred to the Nutrition Service of a private tertiary care hospital in the Philippines.

Methods: A review of medical records was done among  patients referred to Clinical Nutrition physicians of St. Luke's Medical Center-Quezon City from January 2013 to September 2014. Descriptive evaluation was done which included nutrition score, weight loss, subjective global assessment score and electrolyte abnormalities.

Results: A total of 30 patients were included for review had low serum phosphorus wthin the first 72 hours of admission and an SGA C grade upon assessment. All patients were noted to have been placed on 20 kcal and above per kg body weight caloric requirement prior to referral. There were 47% underweight patients, 70% had suboptimal intake while 27% had starvation by nutrition history. Majority of the patients had cancer, 11 of which underwent either chemotherapy or radiotherapy and 8 patients underwent major surgery. Of the total 30 patients with hypophosphatemia within the 24-72-hour period of initiation of nutrition support, a total of 9 patients were seen to have an established drop in serum phosphorus levels based on two succeeding blood determination.

Conclusion: Refeeding hypophosphatemia exists in clinical practice and awareness on the risks and complications of refeeding syndrome should be a vital part of nutrition management.